Individuals with OA of the hip or knee experience discomfort, reduced muscle power, decreased range of joint motion, and joint instability. According to the World Health Organization OA is among the ten most disabling diseases in developed countries. Further WHO estimates state that 80 percent of those with OA have limitations in movement, and 25 percent cannot perform major lifestyle activities. Often OA patients are referred to physical therapy to be able to decrease impairments and improve overall physical function to meet demands of daily living. Although workout therapy has beneficial short-term effects, ealier research shows that after discharge of workout therapy the positive treatment effects decline over time and lastly disappear in the long-term.To accelerate study in hepatobiliary cancers, this Symposium shall generate an inclusive community that may identify strategies to overcome traditional medical analysis silos. My goal jointly is that, the Symposium assembly will continue to work collaboratively to create a roadmap to improve the treatment plans for individuals with gallbladder and bile duct cancers. The Symposium agenda contains expert panel discussions, interactive exchanges to facilitate cross-discipline learning and Research Team group work. CanLiv will award its inaugural 2010 Translational Analysis Grants at the final outcome of the Symposium.